منابع مشابه
Permeability of Erythrocytes to Radioactive Potassium
The diffusion coefficients for the exchange of potassium across the membrane of erythrocytes of humans, rats, and rabbits have been determined by the use of artificially radioactive potassium, both into and out of the erythrocytes both in vitro and in vivo. The diffusion coefficients found in minutes(-1) were 0.2 to 0.25 x 10(-3) for human, 0.32 to 0.665 x 10(-3) for rabbits, and 1.0 x 10(-3) f...
متن کاملDecreased water and potassium content in erythrocytes in essential hypertension.
The water content in erythrocytes of subjects with borderline or established essential hypertension was measured by using gas-liquid chromatography and was found to be lower than that in normotensive controls (p less than 0.01). The water content in erythrocytes of normal controls (n = 14), borderline hypertensive subjects (n = 18), and established essential hypertensive subjects (n = 23) was (...
متن کاملEffect of cetiedil on cation and water movements in erythrocytes.
Cetiedil is a potential antisickling agent whose major effect appears to be at the erythrocyte membrane. To test the hypothesis that cetiedil alters cation transport, we studied the effect of the drug in promoting changes in cell water (Wc), cell sodium (Nac), and cell potassium (Kc). Results are quite different depending on the presence or near absence of intracellular ATP. With fresh cells, 1...
متن کاملChloride-activated passive potassium transport in human erythrocytes.
Passive K+ transport in human erythrocytes (defined as ouabain-insensitive transport) was inhibited 70% by replacement of Cl- by several permeant monovalent anions. The Vmax of Cl--dependent K+ influx was 1.14 mmol . liter-1, hr-1; its apparent Km for K+ was 4.7 mM. There was a much smaller component of Na+ influx dependent on Cl- (Vmax, 0.23 mmol . liter-1 . hr-1). Furosemide and other inhibit...
متن کاملCharacterisation of the potassium influx in rat erythrocytes.
In the rat erythrocyte membrane five different transport pathways for K+ are present. In addition to the well characterised K+ transport via the Na+ pump, the Na,K,Cl cotransport and the Ca(2+)-activated K+ channel, there are a K,Cl cotransport and a residual (leak) K+ transport. The K,Cl cotransport is already present under physiological conditions, and can be stimulated by N-ethylmaleimide tr...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1955
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1955.sp005371